On June 26th, 2025, India witnessed important developments across various sectors. The nation has recently achieved a significant milestone by breaking into the top 100 in the global Sustainable Development Goals (SDG) Index, showcasing its continuous progress in vital development areas. This comes alongside exciting advancements in climate solutions, with India experimenting with Enhanced Rock Weathering for carbon capture, and breakthroughs in medical science, as a new technique for In Vivo CAR T-cells promises to make advanced cancer therapy more accessible and affordable.
Awareness regarding daily UPSC current affairs is crucial for cracking the UPSC Prelims, excelling in UPSC Mains. It helps perform well in the UPSC personality test, thus becoming an informed and effective UPSC civil servant.
Below are the current affairs and headlines of the day taken from The Hindu, Indian Express, Press Information Bureau & All India Radio as required for UPSC preparation:
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Source: The Hindu
Syllabus: GS Paper III (Economy)
India has for the first time entered the top 100 countries in the global Sustainable Development Goals (SDG) Index. This is a major achievement that shows India's hard work in meeting global development goals.
The Sustainable Development Report (SDR) is an important yearly report that checks how well countries are doing on the Sustainable Development Goals (SDGs).
The 2025 report shows good news for India:
Here's how India compares to some other countries in its region and beyond:
Country |
Rank |
SDG Score |
China |
49 |
74.4 |
USA |
44 |
75.2 |
Bhutan |
74 |
70.5 |
Nepal |
85 |
68.6 |
India |
99 |
67 |
Bangladesh |
114 |
63.9 |
Pakistan |
140 |
57 |
The report shows that overall, the world is not doing very well in achieving the SDGs by the target year of 2030:
What are Sustainable Development Goals (SDGs)?The Sustainable Development Goals (SDGs) are a set of global goals for a better world.
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Source: The Hindu
Syllabus: GS Paper I (Geography)
What is Carbon Capture?Carbon capture refers to special technologies or natural ways that are designed to take CO2 out of the air and store it permanently. This helps to reduce the amount of greenhouse gases that cause global warming.
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ERW is a climate change solution that tries to make the natural breakdown of rocks happen much faster. The goal is for these rocks to absorb more CO2 from the atmosphere.
The process of Enhanced Rock Weathering (ERW) involves a few simple steps:
Know what Carbon Sequestration is!
Enhanced Rock Weathering offers several important benefits for fighting climate change and improving agriculture:
Source: The Hindu
Syllabus: GS Paper III (Science & Technology)
A new study published in June 2025 in the scientific journal 'Science' has introduced a major breakthrough in cancer treatment. Researchers from the U.S. National Institutes of Health (NIH), Capstan Therapeutics, and the University of Pennsylvania have found a new way to create special cancer-fighting cells directly inside the body. This new method is called In Vivo CAR T-cell engineering. This discovery could greatly reduce the cost, make the treatment less complex, and lead to fewer side effects compared to the traditional CAR T-cell therapy. The current therapy is very expensive and needs special labs, which limits its use, especially in countries like India.
What is CAR T-cell Therapy?CAR T-cell therapy is a very advanced type of cancer treatment that uses the body's own immune system to fight cancer. It is a form of immunotherapy.
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The traditional way of making CAR T-cells (called ex vivo) involves taking T-cells out of the patient's body, changing them in a lab, growing many of them, and then putting them back. This is a complex, long, and costly process.
The new In Vivo CAR T-cell Engineering method changes this significantly:
The new In Vivo CAR T-cell engineering platform offers significant advantages over the conventional CAR T-cell therapy:
Parameter |
Conventional CAR T-cell Therapy |
New In Vivo Platform |
Manufacturing |
Complex, multi-step process done in a lab |
Simpler, directly engineered inside the body (in vivo) |
Cost (India) |
Very high, about ₹60–70 lakh (approx. $7,200-$8,400 USD) |
Significantly lower than the conventional method |
Chemotherapy (Prep) |
Needed (patients undergo lymphodepletion to reduce existing immune cells) |
Not required (eliminates the need for chemotherapy as preparation) |
Speed of Delivery |
Weeks (due to extensive lab work, cell growth) |
Much faster – just a few intravenous (IV) infusions |
Type of Gene Delivery |
Uses viral vectors (which carry a small risk of integrating into the patient's DNA) |
Uses mRNA (non-integrating, lower genetic risks) |
Safety Profile |
Risk of severe side effects like Cytokine Release Syndrome (CRS) and infections |
Lower genetic risks; main side effects seen are mild liver effects |
🎯Question 1:
With reference to the Global Sustainable Development Goals (SDG) Index, consider the following statements:
Which of the statements given above is/are correct?
(a) 1 only
(b) 1 and 2 only
(c) 2 and 3 only
(d) 1, 2 and 3
✅Correct Answer: (d)
ℹ️Explanation:
🎯Question 2:
Regarding Enhanced Rock Weathering (ERW) as a carbon dioxide removal (CDR) strategy, which of the following statements is/are correct?
Select the correct answer using the code given below:
(a) 1, 2 and 3 only
(b) 2, 3 and 4 only
(c) 1 and 4 only
(d) 1, 2, 3 and 4
✅Correct Answer: (d)
ℹ️Explanation:
🎯Question 3:
With reference to In Vivo CAR T-cell engineering, which of the following statements correctly describes a key aspect of this new technique?
(a) It involves extracting T-cells from the patient, modifying them in a lab, and then reinfusing them.
(b) It uses traditional viral vectors for genetic modification to ensure higher safety and integration.
(c) It generates CAR T-cells directly inside the body using mRNA instructions delivered by lipid nanoparticles.
(d) Its primary benefit is a significant increase in the overall cost of CAR T-cell therapy.
✅Correct Answer: (c)
ℹ️Explanation:
🎯Question 4:
According to the 2025 Sustainable Development Report, India needs to intensify its focus on which of the following Sustainable Development Goals (SDGs)?
Select the correct answer using the code given below:
(a) 1 and 2 only
(b) 1, 2 and 3 only
(c) 3 and 4 only
(d) 1, 2, 3 and 4
✅Correct Answer: (b)
ℹ️Explanation:
The article specifically lists "Climate action (SDG 13), Gender equality (SDG 5), Life below water (SDG 14) and Life on land (SDG 15), Sustainable cities (SDG 11)" as areas where India needs to intensify focus. Responsible Consumption and Production (SDG 12) is not explicitly mentioned in this list within the provided text. Therefore, statements 1, 2, and 3 are correct.
🎯Question 5:
Which of the following are mentioned as benefits of Enhanced Rock Weathering (ERW)?
Select the correct answer using the code given below:
(a) 1 and 2 only
(b) 3 and 4 only
(c) 1, 2 and 3 only
(d) 1, 2, 3 and 4
✅Correct Answer: (d)
ℹ️Explanation:
All four points are benefits of ERW:
Monthly Current Affairs |
UPSC Current Affairs for June 2025 |
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