Complementary ds RNA which prevents translation is formed in ________.

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CUET Biology 23rd Aug 2022 Official Paper
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  1. PCR
  2. RNA interference
  3. Gene therapy
  4. ELISA

Answer (Detailed Solution Below)

Option 2 : RNA interference
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Detailed Solution

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Key Points
  • RNA interference (RNAi) is a post-transcriptional process, that inhibits the translation of mRNA into its proteins.
  • It helps in regulating the activity of the genes by silencing or deactivating the genes.
  • This technology is used to obtain disease resistance in some plants.
  • After an infection, the pathogen produces RNA in the host cell to express toxins, produce more progeny, virus coat protein, etc.
  • This RNA produced by the infectious agent can be silenced using a complementary dsRNA produced by the host.
  • This dsRNA, helps in recognizing and transferring to the target RNA from nematodes, bacteria, or viruses.
  • One of the strands is degraded and a single-stranded complementary RNA binds to the target RNA.
  • The binding of ssRNA (from host) prevents the translation of the mRNA (silencing).

Hence, the correct answer is option 2.

F2 Madhuri Teaching 01.06.2022 D1

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