Match the names of the scientists with their contributions and choose the correct answer.

Column-I

Contributions

Column-II

Name of scientists

A.

PCR

(i)

Hershey & Chase

B.

DNA Fingerprinting

(ii)

Kary Mullis

C.

DNA genetic material

(iii)

Messelson & Stahl

D.

Semiconservative replication

(iv)

Alec Jeffreys

 

 

 

 

 

 

 

 

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  1. A-(iii), B-(ii), C-(iv), D-(i)
  2. A (ii), B-(iv), C-(i), D-(iii)
  3. A-(ii), B-(iii), C-(i), D-(iv) 
  4. A-(ii), B-(iv), C-(iii), D-(i)

Answer (Detailed Solution Below)

Option 2 : A (ii), B-(iv), C-(i), D-(iii)
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Detailed Solution

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The correct answer is A-(ii), B-(iv), C-(i), D-(iii).

Explanation:

  • A. PCR - Kary Mullis (ii):
    • Polymerase Chain Reaction (PCR) is a technique used to amplify a segment of DNA, producing millions of copies of a particular DNA sequence.
    • Kary Mullis developed the PCR technique in 1983, which revolutionized molecular biology and genetic research.
  • B. DNA Fingerprinting - Alec Jeffreys (iv):
    • DNA fingerprinting is a method used to identify individuals based on their unique DNA profiles.
    • Alec Jeffreys developed DNA fingerprinting in 1984, which has applications in forensic science, paternity testing, and genetic studies.
  • C. DNA as genetic material - Hershey & Chase (i):
    • In 1952, Alfred Hershey and Martha Chase conducted experiments using bacteriophages to demonstrate that DNA is the genetic material, not protein.
  • D. Semiconservative replication - Meselson & Stahl (iii):
    • Matthew Meselson and Franklin Stahl conducted experiments in 1958 that demonstrated DNA replication is semiconservative. This means that each new DNA molecule consists of one old strand and one new strand.
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